Stromal targeted therapy in bone metastatic prostate cancer: promise delivered
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چکیده
منابع مشابه
Stromal targeted therapy in bone metastatic prostate cancer: promise delivered.
T he ability of epithelial neoplasms to evade both hormonal and cytotoxic therapies is self-evident as the common carcinomas (lung, stomach, breast, colon and prostate) at their metastatic stage are rarely curable with current therapies. Though the precise reasons for incurability are debated, virtually all agree that tumor genetic heterogeneity makes eradication of the tumor difficult given ‘D...
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only orchiectomy is still commonly used today either as a single therapy or in combination regimens. hypophysectomy & adrenalectomy showed such devastating effects on the endocrine equilibrium as to be inconsistent with an acceptable quality of life or even with survival. chemical adrenalectomy was also tried with drugs (eg. aminoglutethmide, spironolactone) leading to consequences superimposab...
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ژورنال
عنوان ژورنال: Asian Journal of Andrology
سال: 2011
ISSN: 1008-682X,1745-7262
DOI: 10.1038/aja.2011.120